In a latest article printed in Vitamins, researchers used bibliometrics, a quantitative evaluation technique, to research the previous 30 years (1993–2023) of information from the Net of Science Core Assortment (WoSCC) database describing the results of dietary patterns on inflammatory bowel illness (IBD).
Research: Impact of Dietary Patterns on Inflammatory Bowel Illness: A Machine Studying Bibliometric and Visualization Evaluation. Picture Credit score: sdecoret/Shutterstock.com
Background
The prevalence of IBD, together with ulcerative colitis (UC) and Crohn’s illness (CD), is growing globally, however its etiology is much less understood.
Amongst others, dietary patterns have acquired essentially the most consideration as an environmental issue associated to the prevalence of IBD. A number of latest research have proven that prime sugar, excessive fats, excessive salt, and low fiber diets improve the chance of IBD.
Regardless of the well-recognized significance of weight loss plan adjustment and dietary interventions in IBD, no bibliometric evaluation has ever been undertaken on this essential analysis subject of medication.
Bibliometrics can reveal analysis hotspots and traits and assist current abstract statistics and analyses of quotation relationships, authors, key phrases, and different knowledge within the printed literature.
In regards to the examine
Within the current examine, researchers first retrieved 1,092 related papers from the WoSCC database associated to the results of weight loss plan on IBD. Subsequent, they used the R language (v 4.3.0) bibliometrix bundle (v 4.1.2) and CiteSpace (v 6.1.R6) to research plain textual content information, and VOSviewer (v 1.6.19) and the On-line Evaluation Platform for Bibliometrics (OALM) for tab-delimited information of the entire information and cited references, which fetched 1,074 paperwork from the 1993–2023 interval for evaluation.
All 4 bibliometric evaluation instruments served a novel perform. As an example, the OALM platform helped with the connection community evaluation and CiteSpace with co-occurrence, cluster, and emergent analyses. Likewise, VOSviewer and the bibliometrix bundle helped the researchers do co-occurrence and cluster analyses and frequency, relational community, and geographic visualization analyses, respectively.
The researchers additionally used Journal Quotation Report (JCR) 2021 version to doc the journal identify, affect issue (IF), and rating.
Outcomes
The event of this analysis subject had two outstanding durations: a sluggish developmental stage between 1993 and 2006 and a big development stage after 2006. The expansion of related publications on this subject conformed to Value’s literature development curve; thus, one may anticipate speedy development in such analysis papers even sooner or later.
Subrata Ghosh and Antonio Gasbarrini had the best educational affect on this analysis subject, adopted by Lee D., whose analysis can also be well known by different researchers. Notably, their analysis conformed to the generalized Lotka’s regulation.
Ghosh S.’s consultant work describes how the intestinal microbiome impacts human temper, conduct, immunity, and IBD.
Gasbarrini A. launched the variations in intestine microbiota in people with various diets, stress ranges, ailments, and antibiotic utilization.
In one other examine, Gasbarrini A. reviewed the results of various dietary elements on the intestinal microbiome. He discovered that plant proteins, corresponding to polyphenols, micronutrients, and so forth., profit intestinal well being. The authors’ clustering evaluation uncovered that the connection between IBD and dietary patterns was related to intestine microbiota and lipids.
Of 72 international locations, the USA of America (USA) contributed essentially the most, whereas China is quickly gaining momentum lately. Harvard College ranked first within the variety of analysis papers and node centrality to emerge as the highest institute on this analysis subject.
All extremely cited research (n=15) coated the epidemiological standing of IBD globally, dietary patterns that mitigated or aggravated the results of IBD, and the connection between dietary patterns and intestinal microbiota.
Research with most rising and core references associated to intestine flora had the best frequency, suggesting that intestinal microbes are an essential focus of analysis when exploring the results of dietary patterns on IBD. The journal evaluation uncovered that analysis on this subject and its sources have been more likely to be printed in high-impact journals, most of which have been JCR Q1 journals.
By means of key phrase cluster evaluation, the authors recognized research evaluating dietary patterns useful or detrimental to IBD sufferers, and a few research additionally examined IBD ailments. These research demonstrated that in UC sufferers, intestine microflora acted on dietary fibers to supply short-chain fatty acids (SCFAs) that interacted with G protein-coupled receptor 43, a course of having useful results on intestine inflammatory ailments.
The emergent evaluation revealed that early research on this analysis subject targeted on the medical and pathological traits of IBD-associated ailments; through the medieval phases, the analysis targeted on IBD danger elements and pathophysiological processes. Nevertheless, intestine microbiota is the present analysis focus, and this sample would possible proceed.
Research have been exploring the molecular mechanism via which dietary patterns have an effect on IBD and located that nuclear issue kappa B (NF-κB), oxidative, and endoplasmic reticulum stresses performed a key function in these processes. As an example, a preclinical examine confirmed that oxyberberine mediates inhibition of the NF-κB pathway to enhance UC in rats. Likewise, the Mediterranean weight loss plan reduces inflammatory biomarkers in IBD sufferers and improves IBD-related ailments, e.g., non-alcoholic fatty liver illness, partially by altering the intestine microbiota.
Conclusions
The examine outcomes supplied a theoretical foundation for follow-up research on the results of dietary habits on IBD. Wholesome consuming and dwelling habits might assist handle IBD, scale back the medical, social, and monetary burden of IBD globally, and enhance the life high quality of IBD sufferers.
Additional, the outcomes confirmed that adherence to a Mediterranean weight loss plan might considerably profit IBD sufferers. Amongst dietary elements: fatty acids, inulin-type fructans, and carbohydrates have been intently associated to IBD. Future analysis would most probably give attention to the recognized sizzling spots, together with intestinal microbiota, fatty acids, NF-κB, and oxidative and endoplasmic reticulum stresses.
